Cigarettes Worsen Symptoms of MS

Whereas 96 participants were active smokers, who were smoking More than 10 Cigarettes daily in three months before the study began. ...

People suffering from multiple sclerosis (MS) who also smoke, face a greater risk of brain tissue shrinkage, which is an outcome of MS. The finding is supported by a new research performed at the Buffalo Neuroimaging Analysis Center (BNAC) at the University at Buffalo. The research is based on magnetic resonance imaging (MRIs) of smokers and nonsmokers in 368 MS patients, who were treated at UB's Jacobs Neurological Institute.
Robert Zivadinov, M.D., Ph.D., professor of neurology at UB, director of the BNAC, and first author on the study said, "Cigarette smoke has many properties that are toxic to the central nervous system, and cigarette smoking has been linked to higher susceptibility and risk of progressive multiple sclerosis. Interactions between cigarette smoking and genetic and immunologic factors may point to mechanisms in disease pathogenesis. No previous studies have investigated differences in MRI characteristics between MS cigarette smokers and MS nonsmokers.”
Scientists analyzed people suffering from three most common types of MS. The 253 participants suffeRed from relapsing-remitting MS and experienced severe attacks with complete or partial recovery, 9 participants suffeRed from primary-progressive MS, which worsened from very beginning. 90 participants experienced secondary-progressive MS, which was characterized by sporadic attacks and continual progression. Other 16 participants experienced their first onset of the disease.
These participants were in the age group of 35-55 years, and suffeRed from MS for an average period of 13 years. The study found that 128 participants were habitual smokers. Whereas 96 participants were active smokers, who were smoking More than 10 Cigarettes daily in three months before the study began. 32 participants were ex-smokers, who had smoked for 6 months or More in the past. Remaining 240 participants had no exposure to active smoking.
The study revealed that there was no significant disparity between smokers and nonsmokers based on various factors, such as age, duration of the disease, course of the disease, and use of drugs.


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